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Postoperative seizure freedom does not normalize altered connectivity in temporal lobe epilepsy

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Specific changes in the functional connectivity of brain networks occur in patients with epilepsy. Yet whether such changes reflect a stable disease effect or one that is a function of… Click to show full abstract

Specific changes in the functional connectivity of brain networks occur in patients with epilepsy. Yet whether such changes reflect a stable disease effect or one that is a function of active seizure burden remains unclear. Here, we longitudinally assessed the connectivity of canonical cognitive functional networks in patients with intractable temporal lobe epilepsy (TLE), both before and after patients underwent epilepsy surgery and achieved seizure freedom.

Keywords: lobe epilepsy; seizure; seizure freedom; temporal lobe

Journal Title: Epilepsia
Year Published: 2017

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