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Inhibition of microRNA‐134 by an oligonucleotide antagomir (ant‐134) has been shown to produce powerful antiseizure effects in multiple models of epilepsy. However, to successfully translate the treatment to the clinic,… Click to show full abstract
Inhibition of microRNA‐134 by an oligonucleotide antagomir (ant‐134) has been shown to produce powerful antiseizure effects in multiple models of epilepsy. However, to successfully translate the treatment to the clinic, it is important to assess what potential adverse effects it may have on naive brain tissue.
Keywords:
microrna 134;
spared ca1;
ca1 pyramidal;
function hippocampal;
neuron function;
pyramidal neuron
Journal Title: Epilepsia
Year Published: 2018
Link to full text (if available)
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Journal Title: Epilepsia
Year Published: 2018
Link to full text (if available)
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recommendations!