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Inhaled alprazolam rapidly suppresses epileptic activity in photosensitive participants

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Treatment options for seizure clusters are limited; the need for easy‐to‐administer treatments remains. The Staccato system delivers drug deep into the lung via inhalation. In this phase 2a study, we… Click to show full abstract

Treatment options for seizure clusters are limited; the need for easy‐to‐administer treatments remains. The Staccato system delivers drug deep into the lung via inhalation. In this phase 2a study, we investigated the ability of three different doses of Staccato alprazolam to suppress the electroencephalographic (EEG) photoparoxysmal response (PPR) compared with placebo in participants with photosensitive seizures.

Keywords: alprazolam rapidly; rapidly suppresses; suppresses epileptic; inhaled alprazolam; activity photosensitive; epileptic activity

Journal Title: Epilepsia
Year Published: 2019

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