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Volume change in amygdala enlargement as a prognostic factor in patients with temporal lobe epilepsy: A longitudinal study

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Considering the clinical heterogeneity of temporal lobe epilepsy with amygdala enlargement (TLE‐AE), identifying distinct prognostic subgroups of TLE‐AE has clinical implications. Until now, baseline volume of the enlarged amygdala (EAV)… Click to show full abstract

Considering the clinical heterogeneity of temporal lobe epilepsy with amygdala enlargement (TLE‐AE), identifying distinct prognostic subgroups of TLE‐AE has clinical implications. Until now, baseline volume of the enlarged amygdala (EAV) has consistently failed to predict prognosis in TLE‐AE. Based on studies suggesting that patients responsive to antiepileptic drugs (AEDs) exhibit remission of AE on follow‐up imaging, we investigated whether reduction rate of EAV is predictive of long‐term prognosis in TLE‐AE.

Keywords: lobe epilepsy; volume change; amygdala enlargement; temporal lobe

Journal Title: Epilepsia
Year Published: 2019

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