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Cortical low‐frequency power correlates with behavioral impairment in animal model of focal limbic seizures

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Impairment in consciousness is a debilitating symptom during and after seizures; however, its mechanism remains unclear. Limbic seizures have been shown to spread to arousal circuitry to result in a… Click to show full abstract

Impairment in consciousness is a debilitating symptom during and after seizures; however, its mechanism remains unclear. Limbic seizures have been shown to spread to arousal circuitry to result in a "network inhibition" phenomenon. However, prior animal model studies did not relate physiological network changes to behavioral responses during or following seizures.

Keywords: cortical low; frequency power; animal model; limbic seizures; low frequency

Journal Title: Epilepsia
Year Published: 2021

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