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Changes in epileptogenicity biomarkers after stereotactic thermocoagulation

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Stereo‐electroencephalography (SEEG)‐guided radiofrequency thermocoagulation (RF‐TC) aims at modifying epileptogenic networks to reduce seizure frequency. High‐frequency oscillations (HFOs), spikes, and cross‐rate are quantifiable epileptogenic biomarkers. In this study, we sought to… Click to show full abstract

Stereo‐electroencephalography (SEEG)‐guided radiofrequency thermocoagulation (RF‐TC) aims at modifying epileptogenic networks to reduce seizure frequency. High‐frequency oscillations (HFOs), spikes, and cross‐rate are quantifiable epileptogenic biomarkers. In this study, we sought to evaluate, using SEEG signals recorded before and after thermocoagulation, whether a variation in these markers is related to the therapeutic effect of this procedure and to the outcome of surgery.

Keywords: thermocoagulation; biomarkers stereotactic; changes epileptogenicity; stereotactic thermocoagulation; epileptogenicity biomarkers

Journal Title: Epilepsia
Year Published: 2021

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