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“Obvious” indications for Neural antibody testing in Epilepsy or Seizures: The ONES checklist

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Numerous predictive scores have been developed to help determine which patients with epilepsy or seizures of unknown etiology should undergo neural antibody testing. However, their diagnostic advantage compared to only… Click to show full abstract

Numerous predictive scores have been developed to help determine which patients with epilepsy or seizures of unknown etiology should undergo neural antibody testing. However, their diagnostic advantage compared to only performing testing in patients with “obvious” indications (e.g., broader features of autoimmune encephalitis, characteristic seizure semiologies) requires further study. We aimed to develop a checklist that identifies patients who have “obvious” indications for neural antibody testing and to compare its diagnostic performance to predictive scores.

Keywords: antibody testing; neural antibody; obvious indications; indications neural; epilepsy seizures

Journal Title: Epilepsia
Year Published: 2022

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