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The Seizure‐Associated Genes Across Species (SAGAS) database offers insights into epilepsy genes, pathways and treatments

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Decades of genetic studies on people with many different epilepsies, and on many nonhuman species, using many different technologies, have generated a huge body of literature about the genes associated… Click to show full abstract

Decades of genetic studies on people with many different epilepsies, and on many nonhuman species, using many different technologies, have generated a huge body of literature about the genes associated with seizures/epilepsy. Collating these data can help uncover epilepsy genes, pathways, and treatments that would otherwise be overlooked. We aimed to collate and structure these data into a database, and use the database to identify novel epilepsy genes and pathways, and to prioritize promising treatments.

Keywords: pathways treatments; seizure associated; database; genes pathways; epilepsy genes; associated genes

Journal Title: Epilepsia
Year Published: 2022

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