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Many pharmacokinetic studies of lacosamide (LCM) have been reported, but no large‐scale clinical study has been conducted on genetic polymorphisms that affect the metabolism of LCM. Therefore, we designed a… Click to show full abstract
Many pharmacokinetic studies of lacosamide (LCM) have been reported, but no large‐scale clinical study has been conducted on genetic polymorphisms that affect the metabolism of LCM. Therefore, we designed a pharmacogenetic study of LCM to explore the effect of genetic polymorphisms on serum LCM concentration. We evaluated the pharmacodynamic characteristics of LCM, including clinical efficacy and toxicity.
Keywords:
pharmacokinetics lacosamide;
genetic polymorphisms;
cyp2c19 genetic;
polymorphisms pharmacokinetics;
effects cyp2c19;
lacosamide korean
Journal Title: Epilepsia
Year Published: 2022
Link to full text (if available)
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Journal Title: Epilepsia
Year Published: 2022
Link to full text (if available)
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recommendations!