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Neurobehavioral deficits and a progressive ictogenesis in the tetrodotoxin model of epileptic spasms

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Our goal was to determine whether animals with a history of epileptic spasms have learning and memory deficits. We also used continuous (24/7) long‐term electroencephalographic (EEG) recordings to evaluate the… Click to show full abstract

Our goal was to determine whether animals with a history of epileptic spasms have learning and memory deficits. We also used continuous (24/7) long‐term electroencephalographic (EEG) recordings to evaluate the evolution of epileptiform activity in the same animals over time.

Keywords: deficits progressive; progressive ictogenesis; tetrodotoxin model; neurobehavioral deficits; ictogenesis tetrodotoxin; epileptic spasms

Journal Title: Epilepsia
Year Published: 2022

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