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Altered cerebellar‐motor loop in benign adult familial myoclonic epilepsy type 1: The structural basis of cortical tremor

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Cortical tremor/myoclonus is the hallmark feature of benign adult familial myoclonic epilepsy (BAFME), the mechanism of which remains elusive. A hypothesis is that a defective control in the preexisting cerebellar‐motor… Click to show full abstract

Cortical tremor/myoclonus is the hallmark feature of benign adult familial myoclonic epilepsy (BAFME), the mechanism of which remains elusive. A hypothesis is that a defective control in the preexisting cerebellar‐motor loop drives cortical tremor. Meanwhile, the basal ganglia system might also participate in BAFME. This study aimed to discover the structural basis of cortical tremor/myoclonus in BAFME.

Keywords: tremor; myoclonic epilepsy; adult familial; benign adult; cortical tremor; familial myoclonic

Journal Title: Epilepsia
Year Published: 2022

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