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Alprazolam administered via the Staccato® breath‐actuated device is delivered into the deep lung for rapid systemic exposure and is a potential therapy for rapid epileptic seizure termination (REST). We conducted… Click to show full abstract
Alprazolam administered via the Staccato® breath‐actuated device is delivered into the deep lung for rapid systemic exposure and is a potential therapy for rapid epileptic seizure termination (REST). We conducted an inpatient study (ENGAGE‐E‐001 [NCT03478982]) in patients with stereotypic seizure episodes with prolonged or repetitive seizures to determine whether Staccato alprazolam rapidly terminates seizures in a small observed population after administration under direct supervision.
Keywords:
staccato alprazolam;
seizure;
seizure termination;
study;
seizure episodes
Journal Title: Epilepsia
Year Published: 2022
Link to full text (if available)
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Journal Title: Epilepsia
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!