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The pharmacokinetics of oral diazepam are affected by food, but food‐effect studies have not been conducted for diazepam nasal spray because it is believed that most absorption occurs via the… Click to show full abstract
The pharmacokinetics of oral diazepam are affected by food, but food‐effect studies have not been conducted for diazepam nasal spray because it is believed that most absorption occurs via the nasal mucosa. However, gastrointestinal side effects reported with nasal diazepam suggest that at least a portion of the drug may be absorbed enterally and thus subject to food effects. The objective of this study was to evaluate the possible effects of food on the pharmacokinetics of diazepam nasal spray in healthy adults.
Keywords:
diazepam nasal;
food;
study evaluate;
nasal spray;
food pharmacokinetics
Journal Title: Epilepsia
Year Published: 2022
Link to full text (if available)
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Journal Title: Epilepsia
Year Published: 2022
Link to full text (if available)
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recommendations!