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Decades of studies have indicated that activation of the deep and intermediate layers of the superior colliculus can suppress seizures in a wide range of experimental models of epilepsy. However,… Click to show full abstract
Decades of studies have indicated that activation of the deep and intermediate layers of the superior colliculus can suppress seizures in a wide range of experimental models of epilepsy. However, prior studies have not examined efficacy against spontaneous limbic seizures. The present study aimed to address this gap through chronic optogenetic activation of the superior colliculus in the pilocarpine model of temporal lobe epilepsy.
Keywords:
optogenetic activation;
activation superior;
model temporal;
superior colliculus;
activation;
pilocarpine model
Journal Title: Epilepsia
Year Published: 2022
Link to full text (if available)
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Journal Title: Epilepsia
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!