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Interictal spikes help localize seizure generators as part of surgical planning for drug‐resistant epilepsy. However, there are often multiple spike populations whose frequencies change over time, influenced by brain state.… Click to show full abstract
Interictal spikes help localize seizure generators as part of surgical planning for drug‐resistant epilepsy. However, there are often multiple spike populations whose frequencies change over time, influenced by brain state. Understanding state changes in spike rates will improve our ability to use spikes for surgical planning. Our goal was to determine the effect of sleep and seizures on interictal spikes, and to use sleep and seizure‐related changes in spikes to localize the seizure‐onset zone (SOZ).
Journal Title: Epilepsia
Year Published: 2022
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