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Quantifying trial‐by‐trial variability during cortico‐cortical evoked potential mapping of epileptogenic tissue

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Measuring cortico‐cortical evoked potentials (CCEPs) is a promising tool for mapping epileptic networks, but it is not known how variability in brain state and stimulation technique might impact the use… Click to show full abstract

Measuring cortico‐cortical evoked potentials (CCEPs) is a promising tool for mapping epileptic networks, but it is not known how variability in brain state and stimulation technique might impact the use of CCEPs for epilepsy localization. We test the hypotheses that (1) CCEPs demonstrate systematic variability across trials and (2) CCEP amplitudes depend on the timing of stimulation with respect to endogenous, low‐frequency oscillations.

Keywords: cortical evoked; trial; variability; quantifying trial; cortico cortical; mapping

Journal Title: Epilepsia
Year Published: 2023

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