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Higher plasma leptin is associated with higher risk of androgenetic alopecia in men

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In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk… Click to show full abstract

In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (AGA). This study aims to investigate the association between plasma leptin level with the risk and severity of AGA in men. Forty‐eight subjects were enrolled including 29 AGA and 19 non‐AGA subjects. The plasma leptin level was significantly higher in AGA subjects, compared to non‐AGA subjects (4.45 vs 2.76 ng/mL, P<.05). A higher plasma leptin levels were positively correlated with the risk of developing AGA in multivariate logistic analysis (odds ratio=2.77, P<.05). Leptin from the circulation might impact the development of AGA.

Keywords: risk; plasma; androgenetic alopecia; aga subjects; higher plasma; plasma leptin

Journal Title: Experimental Dermatology
Year Published: 2017

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