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Anti‐factor VIII antibodies in brothers with haemophilia A share similar characteristics

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The development of neutralizing antibodies (inhibitors) against coagulation factor VIII (FVIII) is currently the most serious complication for patients with haemophilia A undergoing FVIII replacement therapy. Several genetic factors have… Click to show full abstract

The development of neutralizing antibodies (inhibitors) against coagulation factor VIII (FVIII) is currently the most serious complication for patients with haemophilia A undergoing FVIII replacement therapy. Several genetic factors have been acknowledged as risk factors for inhibitor development.

Keywords: antibodies brothers; factor viii; viii antibodies; factor; anti factor

Journal Title: Haemophilia
Year Published: 2017

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