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Long‐term regular administrations of factor VIII (FVIII) concentrate (prophylaxis) initiated at an early age prevents bleeding in patients with severe haemophilia A (HA). The 5‐year prospective Italian POTTER study provided… Click to show full abstract
Long‐term regular administrations of factor VIII (FVIII) concentrate (prophylaxis) initiated at an early age prevents bleeding in patients with severe haemophilia A (HA). The 5‐year prospective Italian POTTER study provided evidence of benefits in adolescents and adults of late prophylaxis (LP) vs. on‐demand therapy (OD) in reducing bleeding episodes and joint morbidity and improving quality of life; however, costs were increased.
Keywords:
late prophylaxis;
effectiveness analysis;
cost effectiveness;
prophylaxis demand;
severe haemophilia
Journal Title: Haemophilia
Year Published: 2017
Link to full text (if available)
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Journal Title: Haemophilia
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!