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Measurement of plasma and platelet tissue factor pathway inhibitor, factor V and Protein S in people with haemophilia

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Tissue factor pathway inhibitor (TFPI) is a naturally occurring anticoagulant found in plasma, where it circulates bound to lipoproteins, factor V (FV) or Protein S (PS), and in platelets. Therapeutic… Click to show full abstract

Tissue factor pathway inhibitor (TFPI) is a naturally occurring anticoagulant found in plasma, where it circulates bound to lipoproteins, factor V (FV) or Protein S (PS), and in platelets. Therapeutic agents targeting TFPI are under development for the treatment of haemophilia A and haemophilia B.

Keywords: factor pathway; pathway inhibitor; tissue factor; factor protein; factor

Journal Title: Haemophilia
Year Published: 2019

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