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Osteoarthritis (OA) and haemophilic arthropathy (HA) are clinically similar, but pathologically distinct conditions which result in joint pain and loss of function. Distinguishing their disease mechanisms is therefore a key… Click to show full abstract
Osteoarthritis (OA) and haemophilic arthropathy (HA) are clinically similar, but pathologically distinct conditions which result in joint pain and loss of function. Distinguishing their disease mechanisms is therefore a key step in the development of curative therapy, as opposed to current symptomatic treatments. A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) 4 is a metzincin‐family member proteoglycan with known local involvement in OA pathogenesis.
Keywords:
possible distinguishing;
adamts possible;
haemophilic arthropathy;
distinguishing indicator;
osteoarthritis haemophilic
Journal Title: Haemophilia
Year Published: 2022
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Journal Title: Haemophilia
Year Published: 2022
Link to full text (if available)
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recommendations!