Despite receiving standard half‐life (SHL) factor VIII (FVIII) concentrates prophylaxis, some severe haemophilia A (HA) patients still encounter spontaneous breakthrough bleeding. Individualized pharmacokinetic (PK)‐guided dosing of extended half‐life (EHL) FVIII… Click to show full abstract
Despite receiving standard half‐life (SHL) factor VIII (FVIII) concentrates prophylaxis, some severe haemophilia A (HA) patients still encounter spontaneous breakthrough bleeding. Individualized pharmacokinetic (PK)‐guided dosing of extended half‐life (EHL) FVIII concentrates may reduce their bleeding events.
               
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