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Older patients with chronic hepatitis C have a lower virological response to interferon (IFN)‐based treatments compared to younger patients. A single nucleotide polymorphism in the IFN‐λ‐4 (IFNL4) gene has a… Click to show full abstract
Older patients with chronic hepatitis C have a lower virological response to interferon (IFN)‐based treatments compared to younger patients. A single nucleotide polymorphism in the IFN‐λ‐4 (IFNL4) gene has a potent predictive effect on treatment response to IFN‐based treatments. The efficacy of simeprevir (SMV) plus pegylated‐IFN (PEG‐IFN) and ribavirin therapy and the predictive value of IFNL4 on the outcome of therapy for older patients have not been addressed.
Keywords:
ifn;
ribavirin therapy;
therapy older;
chronic hepatitis;
older patients
Journal Title: Hepatology Research
Year Published: 2017
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Journal Title: Hepatology Research
Year Published: 2017
Link to full text (if available)
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recommendations!