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Clinical implication of immune checkpoint inhibitor on the chronic hepatitis B virus infection

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The risk of hepatitis B virus (HBV) reactivation with immune checkpoint inhibitors (ICIs) is an important issue that has not yet been fully investigated. ICI is also expected to have… Click to show full abstract

The risk of hepatitis B virus (HBV) reactivation with immune checkpoint inhibitors (ICIs) is an important issue that has not yet been fully investigated. ICI is also expected to have an antiviral effect on HBV due to its immune tolerance inhibitory effect. We herein investigated the risk of HBV reactivation and the antiviral effect of ICI administration.

Keywords: clinical implication; hepatitis virus; immune checkpoint

Journal Title: Hepatology Research
Year Published: 2022

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