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Significant association between HLA‐B*35:01 and onset of drug‐induced liver injury caused by Kampo medicines in Japanese patients

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Drug‐induced liver injury (DILI) is a severe and life‐threatening immune‐mediated adverse effect, occurring rarely among treated patients. We examined genomic biomarkers in the Japanese population that predict the onset of… Click to show full abstract

Drug‐induced liver injury (DILI) is a severe and life‐threatening immune‐mediated adverse effect, occurring rarely among treated patients. We examined genomic biomarkers in the Japanese population that predict the onset of DILI after using a certain class of drugs, such as Kampo products (Japanese traditional medicines).

Keywords: drug induced; liver injury; significant association; induced liver

Journal Title: Hepatology Research
Year Published: 2022

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