Primary biliary cholangitis (PBC) is an autoimmune liver disease marked by progressive bile duct damage, leading to bile retention. Dendritic cells (DCs), as antigen‐presenting cells, are crucial for immune regulation,… Click to show full abstract
Primary biliary cholangitis (PBC) is an autoimmune liver disease marked by progressive bile duct damage, leading to bile retention. Dendritic cells (DCs), as antigen‐presenting cells, are crucial for immune regulation, and their dysfunction is linked to autoimmunity. This study demonstrates that DC‐depleted mice manifest an autoimmune biliary disease resembling human PBC and investigates its mechanism.
Keywords:
disease;
biliary disease;
primary biliary;
biliary cholangitis;
depleted mice;
autoimmune biliary
Journal Title: Hepatology Research
Year Published: 2025
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Journal Title: Hepatology Research
Year Published: 2025
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!