Photo from wikipedia
Human papillomavirus (HPV) is known as causative for squamous cell carcinoma (SCC) of the oropharynx, but is also found not infrequently in carcinomas of the sinonasal tract. Recently, a subset… Click to show full abstract
Human papillomavirus (HPV) is known as causative for squamous cell carcinoma (SCC) of the oropharynx, but is also found not infrequently in carcinomas of the sinonasal tract. Recently, a subset of these carcinomas was recognized to harbour HPV33 and have a significant morphological overlap with adenoid cystic carcinoma (ACC), a rare and aggressive carcinoma originating in the minor salivary glands. Termed ‘HPV‐related carcinoma with ACC‐like features’, only nine cases have been reported. To clarify the occurrence of these tumours we screened a large material for the presence of HPV‐related ACC‐like carcinoma. The identified tumours were characterized immunohistochemically and with fluorescence in‐situ hybridization, and clinicopathological information for all cases is presented.
Journal Title: Histopathology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!