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The treatment of patients with tubo‐ovarian high‐grade serous carcinoma (HGSC) is increasingly based on diagnosis on small biopsy samples, and the first surgical sample is often taken post‐chemotherapy. p53 and… Click to show full abstract
The treatment of patients with tubo‐ovarian high‐grade serous carcinoma (HGSC) is increasingly based on diagnosis on small biopsy samples, and the first surgical sample is often taken post‐chemotherapy. p53 and WT1 are important diagnostic markers for HGSC. The effect of neoadjuvant chemotherapy on p53 and WT1 expression has not been widely studied. We aimed to compare p53 and WT1 expression in paired pre‐chemotherapy and post‐chemotherapy samples of HGSC.
Keywords:
chemotherapy;
p53 wt1;
expression;
ovarian high;
tubo ovarian
Journal Title: Histopathology
Year Published: 2017
Link to full text (if available)
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Journal Title: Histopathology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!