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Atypical intraductal proliferation and intraductal carcinoma of the prostate on core needle biopsy: a comparative clinicopathological and molecular study with a proposal to expand the morphological spectrum of intraductal carcinoma

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Atypical intraductal proliferation (AIP) of the prostate is histologically worse than high‐grade prostate intraepithelial neoplasia, but lacks the diagnostic criteria of intraductal carcinoma of the prostate (IDC‐P). The aim of… Click to show full abstract

Atypical intraductal proliferation (AIP) of the prostate is histologically worse than high‐grade prostate intraepithelial neoplasia, but lacks the diagnostic criteria of intraductal carcinoma of the prostate (IDC‐P). The aim of this study was to compare the clinicopathological and molecular characteristics (ERG overexpression and PTEN loss) of AIP and IDC‐P in core needle biopsies.

Keywords: atypical intraductal; carcinoma; intraductal proliferation; intraductal carcinoma; carcinoma prostate

Journal Title: Histopathology
Year Published: 2017

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