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Clear cell sarcoma of the kidney (CCSK) is a rare paediatric renal malignant tumour. The majority of CCSKs have internal tandem duplications (ITDs) of the BCOR gene, whereas a minority… Click to show full abstract
Clear cell sarcoma of the kidney (CCSK) is a rare paediatric renal malignant tumour. The majority of CCSKs have internal tandem duplications (ITDs) of the BCOR gene, whereas a minority have the YWHAE–NUTM2 gene fusion. A third ‘double‐negative’ (DN) category comprises CCSKs with neither BCOR ITDs nor YWHAE–NUTM2 fusion. The aim of this study was to characterise 11 histologically diagnosed CCSKs immunohistochemically (with CCND1, BCOR and CCNB3 stains) and genetically.
Keywords:
bcor gene;
internal tandem;
clear cell;
fusion;
gene;
tandem duplications
Journal Title: Histopathology
Year Published: 2018
Link to full text (if available)
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Journal Title: Histopathology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!