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Inflammatory myofibroblastic tumour (IMT) is a spindle cell neoplasm of intermediate malignancy, and the diagnosis is often challenging due to the morphological overlap with other spindle cell neoplasms and reactive… Click to show full abstract
Inflammatory myofibroblastic tumour (IMT) is a spindle cell neoplasm of intermediate malignancy, and the diagnosis is often challenging due to the morphological overlap with other spindle cell neoplasms and reactive lesions. More than half of IMTs have the ALK gene rearrangement, and a minor subset have ROS1, NTRK3 or RET gene rearrangements. We sought to determine the potential diagnostic utility of pan‐Trk immunohistochemistry for IMTs.
Keywords:
pan trk;
trk immunohistochemistry;
utility pan;
diagnostic utility;
inflammatory myofibroblastic
Journal Title: Histopathology
Year Published: 2019
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Journal Title: Histopathology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!