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Bilateral multiple oncocytic cysts of the parotid gland in type 2 diabetes patients

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The hallmarks of type 2 diabetes (T2D) are hyperglycaemia and insulin resistance. These factors, at the cellular level, are associated with mitochondrial dysfunction and increased glucose uptake. Such events are… Click to show full abstract

The hallmarks of type 2 diabetes (T2D) are hyperglycaemia and insulin resistance. These factors, at the cellular level, are associated with mitochondrial dysfunction and increased glucose uptake. Such events are poorly explored in the context of the salivary glands. In this study, we present a series of eight cases of a distinct salivary gland lesion characterised by multiple oncocytic cysts, and we provide new pathological insights regarding its pathogenesis.

Keywords: cysts parotid; bilateral multiple; multiple oncocytic; type diabetes; oncocytic cysts; gland

Journal Title: Histopathology
Year Published: 2019

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