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HER2‐amplified cervical gastric‐type mucinous carcinoma with a primitive enterocyte phenotype

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Gastric-type mucinous carcinoma is a subtype of adenocarcinoma of the uterine cervix whose differentiation is characterized by cytoplasmic pyloric gland mucins.1 In the stomach, adenocarcinoma may occasionally show foetal gut… Click to show full abstract

Gastric-type mucinous carcinoma is a subtype of adenocarcinoma of the uterine cervix whose differentiation is characterized by cytoplasmic pyloric gland mucins.1 In the stomach, adenocarcinoma may occasionally show foetal gut differentiation.2 However, such retro-differentiation is rarely reported in cervical gastric-type mucinous carcinoma. Herein, we present a case of gastric-type mucinous carcinoma with a primitive enterocyte phenotype whose clear cell morphology mimicked clear cell carcinoma (CCC) in its preoperative biopsy.

Keywords: carcinoma; cervical gastric; type mucinous; gastric type; mucinous carcinoma

Journal Title: Histopathology
Year Published: 2020

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