LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Taking Tumour Budding to the Next Frontier - a Post-ITBCC 2016 Review.

Tumour budding in colorectal cancer, defined as single tumour cells or small clusters containing four tumour cells or less, is a robust and independent biomarker of aggressive tumour biology. Based… Click to show full abstract

Tumour budding in colorectal cancer, defined as single tumour cells or small clusters containing four tumour cells or less, is a robust and independent biomarker of aggressive tumour biology. Based on published data in the literature, evidence is certainly in favour of reporting tumour budding in routine practice. One important aspect of implementing tumour budding has been to establish a standardized and evidence-based scoring method as has been recommended by the International Tumour Budding Consensus Conference (ITBCC) in 2016. Further developments have aimed at establishing methods of automated tumour budding assessment. A digital approach to scoring tumour buds has great potential to assist in performing an objective budding count, but in analogy to the manual consensus method, must be validated and standardized. The aim of the present review is to present general considerations behind the ITBCC scoring method and a broad overview of the current status quo and challenges faced by automated tumour budding detection methods.

Keywords: tumour budding; taking tumour; review; itbcc 2016; tumour

Journal Title: Histopathology
Year Published: 2020

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.