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DICER1 germline mutations cause DICER1 syndrome, in which multinodular goitre is a common feature. Recently, somatic DICER1 mutations have been reported in sporadic thyroid carcinomas, of which the newly described… Click to show full abstract
DICER1 germline mutations cause DICER1 syndrome, in which multinodular goitre is a common feature. Recently, somatic DICER1 mutations have been reported in sporadic thyroid carcinomas, of which the newly described macrofollicular variant of follicular thyroid carcinoma (MV‐FTC) seems particularly enriched for this aberrancy. We report here histological and genetic findings in five follicular thyroid tumours with macrofollicular architecture (four carcinomas and one adenoma).
Keywords:
tumors dicer1;
variant follicular;
thyroid tumors;
follicular thyroid;
macrofollicular variant;
thyroid
Journal Title: Histopathology
Year Published: 2021
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Journal Title: Histopathology
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!