Photo by nci from unsplash
Recurrent alterations involving receptor tyrosine or cytoplasmic kinase genes have been described in soft‐tissue neoplasms such as infantile fibrosarcoma (IFS) and inflammatory myofibroblastic tumour (IMT). Recent trials and regulatory approvals… Click to show full abstract
Recurrent alterations involving receptor tyrosine or cytoplasmic kinase genes have been described in soft‐tissue neoplasms such as infantile fibrosarcoma (IFS) and inflammatory myofibroblastic tumour (IMT). Recent trials and regulatory approvals for targeted inhibitors against the kinase domains of these oncoproteins have allowed for increased use of targeted therapies. We aimed to characterize the histologic features of paediatric mesenchymal neoplasms with kinase alterations treated with targeted inhibitors.
Journal Title: Histopathology
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!