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Emerging evidence indicates that breast cancer (BC) patients whose tumours express HER2 protein without HER2 gene amplification (HER2‐low), can benefit from antibody–drug conjugates (ADC). However, the current definition of HER2‐low… Click to show full abstract
Emerging evidence indicates that breast cancer (BC) patients whose tumours express HER2 protein without HER2 gene amplification (HER2‐low), can benefit from antibody–drug conjugates (ADC). However, the current definition of HER2‐low BC remains incomplete with low rates of concordance. This study aims to refine HER2‐low definition with emphasis on distinguishing HER2 score 0 from score 1+ to identify patients who are eligible for ADC.
Keywords:
breast cancer;
her2 low;
her2;
definition her2
Journal Title: Histopathology
Year Published: 2022
Link to full text (if available)
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Journal Title: Histopathology
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!