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Expression of paired box 9 defines an aggressive subset of lung adenocarcinoma preferentially occurring in smokers

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A distinct subset of lung adenocarcinomas (LADs), arising from a series of peripheral lung cells defined as the terminal respiratory unit (TRU), is characterised by thyroid transcription factor 1 (TTF‐1)… Click to show full abstract

A distinct subset of lung adenocarcinomas (LADs), arising from a series of peripheral lung cells defined as the terminal respiratory unit (TRU), is characterised by thyroid transcription factor 1 (TTF‐1) expression. The clinical relevance of transcription factors (TFs) other than TTF‐1 remains unknown in LAD and was explored in the present study.

Keywords: lung; subset lung; paired box; expression paired

Journal Title: Histopathology
Year Published: 2022

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