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Genetic and epigenetic analysis of hepatocellular adenomas with atypical morphological features

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Hepatocellular adenoma (HCA) is a rare liver tumour, which can have atypical morphological features such as cytological atypia, pseudoglandular architecture, and altered reticulin framework. Little is known about the genetic… Click to show full abstract

Hepatocellular adenoma (HCA) is a rare liver tumour, which can have atypical morphological features such as cytological atypia, pseudoglandular architecture, and altered reticulin framework. Little is known about the genetic and epigenetic alterations of such HCAs and whether they show the alterations classically found in hepatocellular carcinoma (HCC) or in HCA without atypical morphology.

Keywords: analysis hepatocellular; epigenetic analysis; atypical morphological; morphological features; hepatocellular adenomas; genetic epigenetic

Journal Title: Histopathology
Year Published: 2022

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