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Grade Group 5 (GG5) prostate cancer (PCa) is associated with a high risk of disease recurrence after radical prostatectomy (~75% at 5 years). However, this is a heterogeneous category that includes… Click to show full abstract
Grade Group 5 (GG5) prostate cancer (PCa) is associated with a high risk of disease recurrence after radical prostatectomy (~75% at 5 years). However, this is a heterogeneous category that includes neoplasms with different combinations of Gleason pattern (GP) 4 and 5. Within GP4, large cribriform growth has been associated with adverse disease‐specific outcomes in GG2‐4 PCa. Less is known about the significance of cribriform morphology and the different histologic patterns of GP5 in GG5 PCa.
Keywords:
recurrence radical;
prostate cancer;
cribriform;
radical prostatectomy;
grade group;
cribriform morphology
Journal Title: Histopathology
Year Published: 2023
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Journal Title: Histopathology
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!