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Bictegravir/emtricitabine/tenofovir alafenamide in patients with genotypic NRTI resistance

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Bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) is approved for treatment of HIV without known resistance to its components. Several studies have demonstrated efficacy of B/F/TAF in patients with nucleoside reverse transcriptase inhibitor (NRTI)… Click to show full abstract

Bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) is approved for treatment of HIV without known resistance to its components. Several studies have demonstrated efficacy of B/F/TAF in patients with nucleoside reverse transcriptase inhibitor (NRTI) resistanceā€associated mutations (RAMs), mainly identified by proviral DNA testing, but data on the efficacy of B/F/TAF in patients with NRTI RAMs identified in viraemic plasma are limited.

Keywords: emtricitabine tenofovir; nrti resistance; bictegravir emtricitabine; resistance; tenofovir alafenamide

Journal Title: HIV Medicine
Year Published: 2022

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