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Enlarged rete pegs with excessive accumulation of melanosomes leading to darker aging spots revealed by histomorphological measurements of internal structures of the epidermis.

Various histological studies of facial pigmented spot sites such as solar lentigo have been reported, but few studies have used quantitative indices by histomorphometric analysis of the internal structure of… Click to show full abstract

Various histological studies of facial pigmented spot sites such as solar lentigo have been reported, but few studies have used quantitative indices by histomorphometric analysis of the internal structure of pigmented spot sites using non‐invasive methods. In the present study, to quantitatively elucidate morphological changes in the epidermis in male, darker‐pigmented spots and female, light‐pigmented spots, indices that characterize the internal structure of the epidermis in pigmented spot sites were measured using in vivo confocal laser scanning microscopy (CLSM).

Keywords: pegs excessive; pigmented spot; darker; spot sites; rete pegs; enlarged rete

Journal Title: International journal of cosmetic science
Year Published: 2023

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