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Long‐acting injectable antipsychotics for prevention and management of violent behaviour in psychotic patients

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It has been well established that long‐term antipsychotic treatment prevents relapse, lowers number of rehospitalisations, and also effectively reduces violent behaviour. Although violent behaviour is not a typical manifestation of… Click to show full abstract

It has been well established that long‐term antipsychotic treatment prevents relapse, lowers number of rehospitalisations, and also effectively reduces violent behaviour. Although violent behaviour is not a typical manifestation of schizophrenia or other psychotic disorders, the diagnosis of psychosis increases the overall risk of violence. One of the few modifiable factors of violence risk is adherence with medication. In contrast, non‐adherence with drug treatment and subsequent relapse increases risk of violent acts. Non‐adherence can be addressed partially by long‐acting injectable antipsychotics (LAI). The aim of our review was to examine the role of antipsychotic drugs, especially LAI, in prevention and management of violent behaviour in psychosis.

Keywords: injectable antipsychotics; prevention management; long acting; behaviour; violent behaviour; acting injectable

Journal Title: International Journal of Clinical Practice
Year Published: 2017

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