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Cariprazine for bipolar depression: What is the number needed to treat, number needed to harm and likelihood to be helped or harmed?

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Cariprazine is an oral antipsychotic approved in the US for the treatment of schizophrenia, acute bipolar mania, and most recently, bipolar depression. The aim of this systematic review is to… Click to show full abstract

Cariprazine is an oral antipsychotic approved in the US for the treatment of schizophrenia, acute bipolar mania, and most recently, bipolar depression. The aim of this systematic review is to describe the efficacy, tolerability and safety of cariprazine for the treatment of depressive episodes associated with bipolar I disorder (bipolar depression) in adults.

Keywords: depression number; bipolar depression; cariprazine bipolar; number; number needed

Journal Title: International Journal of Clinical Practice
Year Published: 2019

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