A 50-year-old man with a history of ischemic heart disease, insulin-requiring diabetes mellitus type II, hypertriglyceridemia, and history of pancreatitis developed skin changes in areas of recent cat scratches (Fig.… Click to show full abstract
A 50-year-old man with a history of ischemic heart disease, insulin-requiring diabetes mellitus type II, hypertriglyceridemia, and history of pancreatitis developed skin changes in areas of recent cat scratches (Fig. 1). Subsequently, similar yellow papules arose in insulin injection sites on the abdomen and blood glucose test sites on the fingertips. These skin changes failed to improve with a 6-week course of doxycycline and a 3-week trial of clobetasol ointment provided to him as empiric therapy by his primary care provider. Physical examination revealed multiple small yellow papules in a linear configuration on the arms, fingertips, abdomen, back, and ankles. Biopsy from one of the forearm papules showed a dermal aggregate of xanthomatized histiocytes (Fig. 2). The patient was diagnosed with eruptive xanthomatosis with koebnerization.
               
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