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Statin‐induced dermatomyositis for the practicing dermatologist: a review of the literature

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Statins cause a spectrum of muscle‐related adverse events, including autoimmune myopathies such as dermatomyositis (DM). This review aims to describe the events of statin‐induced DM and amyopathic dermatomyositis (ADM) to… Click to show full abstract

Statins cause a spectrum of muscle‐related adverse events, including autoimmune myopathies such as dermatomyositis (DM). This review aims to describe the events of statin‐induced DM and amyopathic dermatomyositis (ADM) to increase awareness for practicing dermatologists about harmful interactions with the most commonly prescribed lipid‐lowering medication. PubMed was searched for relevant literature related to statin‐induced DM and ADM. Numerous cases of statin‐induced DM have been reported in individuals with no history of DM or other autoimmune conditions. Statins also cause ADM, although this is a rare association. Because of the widespread use of statins worldwide for atherosclerotic disease prevention, it may be of benefit to practicing dermatologists and all clinicians to assess for a history of DM when prescribing statins and inquire if patients with a DM‐like presentation are taking or have taken a statin medication.

Keywords: literature; statin; statin induced; induced dermatomyositis; review

Journal Title: International Journal of Dermatology
Year Published: 2019

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