LAUSR

mon dermoscopic features were uniform dotted vessels and diffuse white scales in psoriasis (Fig. 1b), clustered dotted vessels, patchy white/yellow scales and adherent fabric fibers in eczema (Fig. 1c), and nonspecifically arranged linear vessels along with patchy white scales in patch-stage mycosis fungoides (Fig. 1d). When it comes to the comparative analysis, the presence of white scales in the skin furrows and the lack of vessels were the most characterizing findings of CSSD compared to all the control groups; moreover, orange structureless areas were also statistically indicative of CSSD when compared to psoriasis and eczema. On the other hand, psoriasis was typified by uniform dotted vessels and diffuse white scales, whereas clustered dotted vessels, adherent fabric fibers, and patchy yellow scales were indicative of eczema and nonspecifically arranged linear vessels of patch-stage mycosis fungoides. Table 1 summarizes all the findings and statistical differences. Figure 1e–h shows histological findings underlying the relevant dermoscopic features of the above-mentioned dermatoses. According to our analysis, although histopathology remains the diagnostic gold standard for the final diagnosis, dermoscopy may be useful to support the diagnosis of CSSD by showing white scales in skin furrows and orange structureless areas, respectively, correlated with patchy hyperparakeratosis and hemosiderin deposits in the dermis on histology. Furthermore, our study also highlighted that, unlike its clinical differential diagnoses, this condition usually does not display any vessel on dermoscopy, likely because of the typical paucity of dermal inflammation/vasodilation. The main limitations of the present study include its retrospective design and the limited sample size, therefore larger studies are needed to confirm our preliminary observations. Additionally, future analyses using higher degrees of magnification (videodermoscopy) will allow a better evaluation of the vascular pattern to assess possible further differences among the considered dermatoses.