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Elevated serum level of B‐cell activating factor (BAFF) after rituximab therapy in pemphigus vulgaris patients suggests a possible therapeutic efficacy of B‐cell depletion therapies combined with anti‐BAFF agents

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Rituximab is widely used for treatment of pemphigus patients. B‐cell activating factor (BAFF) and a proliferation‐inducing ligand (APRIL) play key roles in B cell survival, maturation, and differentiation. Here, the… Click to show full abstract

Rituximab is widely used for treatment of pemphigus patients. B‐cell activating factor (BAFF) and a proliferation‐inducing ligand (APRIL) play key roles in B cell survival, maturation, and differentiation. Here, the effect of rituximab on BAFF and APRIL in patients with pemphigus vulgaris (PV) was studied.

Keywords: cell; baff; cell activating; factor baff; activating factor; rituximab

Journal Title: International Journal of Dermatology
Year Published: 2022

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