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Treatment recalcitrant cases of tinea corporis/cruris caused by T. mentagrophytes – interdigitale complex with mutations in ERG11 ERG 3, ERG4, MDR1 MFS genes & SQLE and their potential implications

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Recalcitrant dermatophyte infections are being reported from various parts of the world due to varied causes including strain variation, steroid misuse, SQLE mutations, and variable quality of itraconazole pellet formulations.… Click to show full abstract

Recalcitrant dermatophyte infections are being reported from various parts of the world due to varied causes including strain variation, steroid misuse, SQLE mutations, and variable quality of itraconazole pellet formulations. The oral drug preferred in endemic areas is itraconazole, to which MIC levels remain low, and clinical failures to itraconazole reported defy a sound scientific explanation.

Keywords: treatment recalcitrant; cases tinea; cruris caused; tinea corporis; corporis cruris; recalcitrant cases

Journal Title: International Journal of Dermatology
Year Published: 2023

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