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The Dapsone Conundrum: Understanding Implications of Adverse Reactions to Dapsone Including Dapsone Hypersensitivity Syndrome in Leprosy Patients Treated With Multidrug Therapy

The introduction of the World Health Organization's multidrug therapy (WHO‐MDT) has significantly advanced leprosy treatment. Although dapsone is a fundamental component of MDT, it presents risks of adverse drug reactions… Click to show full abstract

The introduction of the World Health Organization's multidrug therapy (WHO‐MDT) has significantly advanced leprosy treatment. Although dapsone is a fundamental component of MDT, it presents risks of adverse drug reactions (ADR), including the potentially fatal dapsone hypersensitivity syndrome (DHS).

Keywords: dapsone; multidrug therapy; dapsone hypersensitivity; hypersensitivity syndrome

Journal Title: International Journal of Dermatology
Year Published: 2025

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